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HomeTreatmentDNA Fragmentation Index (DFI) Test

DNA Fragmentation Index (DFI) Of Sperm – Key To Understanding Male Fertility

  • How it Works
  • Suitable For
  • Process
  • Cost
  • Results
  • Success Rate
  • FAQs

While dealing with unexplained infertility concerns, fertility experts recommend a series of diagnostic tests to identify the potential causes of infertility or recurring failed fertilisation episodes. A DFI test is a diagnostic test that helps fertility experts to identify the potential cause of infertility or recurring failed fertilisation episodes. They study the sperm cells to analyse whether the DFA fragmentation index is within controlled range. Fertility experts at Oasis Fertility specialise in DFI testing to get precise insights into the causes of infertility in male partners. The state-of-the-art facilities and the experience of the fertility specialists combined help couples achieve their parenthood dreams safely.

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What Is DFI Test and How Does It Work?

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DFI stands for DNA Fragmentation Index test and helps identify the extent of DNA fragmentation in a male’s sperm cells. A widely-used test, doctors primarily recommend it for males dealing suffering with infertility issues. The test assesses male fertility to identify potential problems in sperm quality impacting the couple’s ability to conceive. The higher the value of DFI in sperm cells, the more fragmented the DNA is. This test also helps doctors rule out or ascertain the cause of male infertility problems. Fertility Experts at Oasis do the DFI testing with SCSA (Sperm Chromatin Structure Assay), which is more reliable than the more common SCD (Sperm Chromatin Dispersion) test.

What Happens If DNA Fragmentation Is High? & Why DFI Test Is Done?

One can refer to DNA fragmentation as a chemical change in the normal structure of the DNA. This condition can alter the genetic material in the DNA present in the form of single or double strands. If the DNA fragmentation is high, it can lead to several adverse effects related to male reproductive functions, such as reduced potential for fertilisation, abnormal embryonic development, and poor pregnancy outcomes. A DFI test is often recommended for couples dealing with male fertility issues, recurrent miscarriages, failed IVF cycles, poor or arrested embryonic development and conditions such as varicocele and abnormal semen findings.

Step By Step DFI Testing Treatment Process

Here is a step-by-step process of an DFI Testing treatment

  • Pre-Care

  • Treatment

  • Post-Care

How Much Does DFI Test Cost in India?

The cost of a DFI test in India ranges between ₹9000 to ₹12000 depending on the lab location, facilities, and public opinion, which adds to the clinic’s credibility.

What are the causes of high DNA fragmentation?

The treatment offers the following benefits:

Hope for parenthood

IVF is an advanced treatment that provides a ray of hope to couples struggling to achieve pregnancy for years.

Chances of having a healthy baby

The procedure minimises the risk of passing any genetic disorder or chromosomal abnormalities to the baby as the procedure involves transferring the healthiest embryos into a woman's body.

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FAQs on DFI Testing Treatment

What Can Cause A Lesion In The DNA Of Spermatozoa?

How Is A Lesion In Sperm DNA Detected?

How To Improve DNA Fragmentation Index?

What Food Reduces DNA Fragmentation In Sperm?

Can You Get Pregnant With High DFI?

What Vitamins Help With DNA Fragmentation?

Can DNA Damaged Sperm Cause Birth Defects?

Is Sperm DNA Fragmentation Curable?

Dr. Jalagam Kavya Rao

Medically Reviewed by

Dr. Jalagam Kavya Rao

Regional Medical Head & Fertility Specialist

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